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Peyronie’s Disease in London: Assessment and Care Pathway

Writer: Fabio Castiglione
Fabio Castiglione
Nov 22, 2025
4 min read

Updated: Aug 19

Peyronie's disease is a condition that affects many men, causing curvature and discomfort in the penis due to fibrous scar tissue. This can lead to pain, difficulties during intercourse, and emotional distress. Fortunately, there are effective treatments available, especially in London, where specialised clinics offer advanced care tailored to individual needs. Understanding the options and what to expect can help men make informed decisions and address confidence concerns.


Understanding Peyronie's Disease Solutions


Peyronie's disease occurs when fibrous plaques develop inside the penile tissue, causing the penis to bend or curve during an erection. This curvature can vary from mild to severe and may be accompanied by pain or erectile dysfunction. The exact cause is not fully understood, but it is often linked to trauma or injury to the penis, genetics, or certain health conditions.


Treatment options depend on the severity of the condition and how much it affects daily life. In some cases, the disease stabilises or improves without intervention. However, when symptoms persist or worsen, medical treatment is recommended.


Common Symptoms Include:

  • Noticeable curvature of the penis during erection

  • Pain during erections or sexual activity

  • Erectile dysfunction or difficulty maintaining an erection

  • Shortening or narrowing of the penis


Early diagnosis and treatment can prevent progression and improve outcomes. Consulting a specialist in London can provide access to the latest therapies and personalised care plans.




Non-Surgical Peyronie's Disease Treatments


Many men prefer to start with non-surgical options, which can be effective, especially in the early stages of the disease. These treatments aim to reduce pain, improve curvature, and may improve function for selected patients without invasive procedures.


1. Oral Medications

Certain medications may help reduce inflammation and scar tissue formation. Examples include:

  • Potassium para-aminobenzoate (Potaba)

  • Vitamin E supplements

  • Pentoxifylline


While these drugs have varying published outcome data, they are often used alongside other treatments.


2. Injection Therapy

Intralesional medication may be considered for selected Peyronie’s deformities. The aim, evidence, eligibility and availability depend on the specific agent, and any improvement in curvature is usually partial rather than complete.

  • Collagenase Clostridium Histolyticum (Xiaflex)

  • Verapamil

  • Interferon alpha-2b


These injections are typically administered in a clinic over several sessions and have shown under investigation results in improving penile shape and function.


3. Shockwave Therapy

Low-intensity shockwave therapy is a newer, non-invasive treatment that uses sound waves to stimulate tissue repair and reduce plaque size. It is tolerable for some patients, although discomfort can occur and requires recovery needs vary; follow clinical advice.


4. Traction Devices

Penile traction therapy involves wearing a mechanical device that gently stretches the penis over time. This can help reduce curvature and improve length. It requires consistent use, often several hours a day for months.


Each of these treatments has its pros and cons, and a specialist can recommend the best approach based on individual circumstances.




Surgical Options for Peyronie's Disease


When non-surgical treatments are ineffective or the curvature is severe, surgery may be necessary. Surgical procedures aim to correct the deformity and may improve sexual function for selected patients.


Types of Surgery Include:


  • Plication Surgery: This involves shortening the longer side of the penis to straighten it. It is less invasive but may result in some penile shortening.

  • Plaque Incision and Grafting: The surgeon cuts the plaque and inserts a graft to lengthen the shorter side, preserving length but with a more complex procedure.

  • Penile Prosthesis Implantation: For men with erectile dysfunction and severe curvature, a penile implant can straighten the penis and restore erections.


Surgery is usually considered after the disease has stabilised, typically after 12 months from onset. Recovery times vary, and patients should discuss risks and benefits thoroughly with their surgeon.




Finding Expert Care in London


London offers access to some of the best urology and men's health specialists in the UK. Clinics provide comprehensive assessments, including physical exams, ultrasound imaging, and detailed consultations to tailor treatment plans.


If you are seeking effective care, consider visiting a clinic that specialises in peyronie's disease treatment london. These centres combine advanced therapies with experienced medical teams to deliver personalised solutions.


What to Expect at Your Appointment:

  • Detailed medical history and symptom review

  • Physical examination and imaging tests

  • Discussion of treatment options and expected outcomes

  • Support for emotional and psychological aspects of the condition


Early intervention can improve quality of life and reduce complications. Many men find that professional guidance helps them address confidence concerns and improve sexual health.


Living Well with Peyronie's Disease


Managing Peyronie's disease involves more than just medical treatment. Lifestyle changes and emotional support play a crucial role in overall wellbeing.


Practical Tips Include:

  • Open Communication: Talk honestly with your partner about the condition and its impact.

  • Healthy Lifestyle: Maintain a balanced diet, exercise regularly, and avoid smoking to support vascular health.

  • Stress Management: Consider counselling or support groups to address anxiety or depression related to the condition.

  • Follow-Up Care: Regular check-ups with your specialist to monitor progress and adjust treatment as needed.


By combining medical treatment with lifestyle adjustments, men can improve their symptoms and maintain fulfilling relationships.



Peyronie's disease can be challenging, but with the right approach, effective solutions are available. London’s specialised clinics offer a range of treatments tailored to individual needs, helping men may improve function for selected patients and support confidence. If you or someone you know is affected, seeking expert advice early can make a significant difference.

Related guides

Medical review and evidence

Medically reviewed by Dr Fabio Castiglione, Consultant Urologist and Andrologist. Last reviewed: 19 August 2026.

Treatment choice for Peyronie’s disease depends on pain, curvature, erectile function, disease stage and patient goals; outcomes vary.

This article is for general education and is not a diagnosis or individual medical recommendation. A consultation should review medical and sexual history, current medicines, examination findings and tests when clinically indicated.

Clinical sources

About the author

Dr Fabio Castiglione

Consultant Urologist and Andrologist in London. Holistic Andrology, 9 Harley Street, London W1G 9QY.

GMC reference number: 7541824

ORCID: https://orcid.org/0000-0001-8046-1963

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